Is Alzheimers Disease Type 3 Diabetes ?

THE human brain evolved to seek out foods high in fat and sugar. But a preference that started out as a survival mechanism has, in our age of plenty, become a self-destructive compulsion.

It is well known that bad diets can trigger obesity and diabetes. There is growing evidence that they trigger Alzheimer’s disease too, and some researchers now see it as just another form of diabetes.

If correct, this has enormous, and grave, implications. The world already faces an epidemic of diabetes. The prospect of a parallel epidemic of Alzheimer’s is truly frightening, in terms of human suffering and monetary cost.

This outcome will not be easily averted. Few people need to be told that too much high-fat, high-sugar food is a health hazard. And yet sales of fast food remain healthy (or should that be hefty?). Part of the reason is “future discounting”, another evolved feature of the human brain that makes us value short-term rewards over long-term risks.

What can be done? One option is to call in the lawyers. Some moderately successful attempts have already been made to sue food companies for their role in creating the obesity epidemic. If a causal link between fatty, sugary food and Alzheimer’s can be established, it is highly likely that more lawsuits will follow. Such actions have their place, but this is a laborious and expensive way to enact change.

Nor do the policy levers at our disposal appear promising. Public awareness campaigns have been of limited use in reversing the tide of obesity. Will the added threat of dementia prove harder to ignore? “Sin taxes” on unhealthy foods may work – Denmark and a handful of other countries are experimenting with them – but it is not yet clear whether they make any real difference. What’s more, they raise questions about personal responsibility and nanny-statism.

We may be left with only the option of medically blocking either the craving for fast food, or its consequences. That has its own complications, and sidesteps the problem rather than addressing it. But the human brain also evolved to find ingenious solutions to intractable problems. It may yet come to its own rescue.

The Brains Drain System

The brain drain is real. There is a network of previously unrecognised vessels that rid the brain of unwanted extracellular fluids and other substances, including amyloid-beta – a peptide that accumulates in the brain of people with Alzheimer’s. The new discovery looks set to add to our understanding of the disease.

Jeffrey Iliff at the University of Rochester Medical Centre, New York, and his colleagues, were intrigued by the fact that there are no obvious lymphatic vessels in the brain. Among other things, the lymphatic system removes waste interstitial fluids from body tissue.

“It seemed strange that such an important and active organ wouldn’t have a specialised waste-removal system,” says Iliff.

When the researchers added fluorescent and radioactive tracers to the cerebrospinal fluid of live mice, the tracers quickly spread throughout the rodents’ brains. Using two-photon microscopy to visualise the movement in real-time, the team saw cerebrospinal fluid permeating the entire brain through ‘pipes’ surrounding blood vessels, similar to the lymphatic system that services all other organs.

The pipes work on hydraulic principles, though, and so the system breaks upon opening, making it hard to identify it outside living organisms.

Exercise – Probably the best Medicine of all

From dementia and diabetes to high blood pressure – no pill protects us against ill health like exercise does.

A plethora of recent studies shows that exercise protects us from heart attacks, strokes, diabetes, obesity, cancer, Alzheimer’s disease and depression. It even boosts memory. And it has the potential to prevent more premature deaths than any other single treatment, with none of the side effects of actual medication. “It’s a wonder drug,” says Erik Richter, a diabetes researcher at the University of Copenhagen, Denmark. “There’s probably not a single organ in the body that’s unaffected by it.”

Throughout evolution, humans have been active. Our ancestors chased prey as hunter-gatherers and fled from predators. More recently, they laboured on farms and in factories. But the decline of agricultural and industrial labour, plus the invention of the car, a multitude of labour-saving devices and – most perniciously – TV, computers and video games, mean we’ve all ground to a sudden and catastrophic standstill.

“We were built to be active, but the way our environment has changed and the way we live our lives has led us to become inactive,” says Christopher Hughes, senior lecturer in sport and exercise medicine at Queen Mary, University of London.

Michael Mosley on intermittent Fasting

Scientists are uncovering evidence that short periods of fasting, if properly controlled, could achieve a number of health benefits, as well as potentially helping the overweight, as Michael Mosley discovered.

I’d always thought of fasting as something unpleasant, with no obvious long term benefits. So when I was asked to make a documentary that would involve me going without food, I was not keen as I was sure I would not enjoy it.

But the Horizon editor assured me there was great new science and that I might see some dramatic improvements to my body. So, of course, I said, “yes”.

I am not strong-willed enough to diet over the long term, but I am extremely interested in the reasons why eating less might lead to increased life span, particularly as scientists think it may be possible to get the benefits without the pain.

How you age is powerfully shaped by your genes. But there’s not much you can do about that.

Calorie restriction, eating well but not much, is one of the few things that has been shown to extend life expectancy, at least in animals. We’ve known since the 1930s that mice put on a low-calorie, nutrient-rich diet live far longer. There is mounting evidence that the same is true in monkeys.

Extreme Exercise and Heart Disease

Extreme exercise such as marathons may permanently damage the heart and trigger rhythm abnormalities, warn researchers. They say the safe ‘upper limit’ for heart health is a maximum of an hour a day – after which there is little benefit to the individual.

A review of research evidence by US physicians says intensive training schedules and extreme endurance competitions can cause long-term harm to people’s hearts. Activities such as marathons, iron man distance triathlons, and very long distance bicycle races may cause structural changes to the heart and large arteries, leading to lasting injury.

Chronic Hidden Hyperventilation – A 21st Century Epidemic ?

This video will explain the importance of a widespread health problem in the West that is rarely diagnosed and even when it is recognised, is usually not helped or guidance given to the patient. The subject is chronic hidden hyperventilation (CHHV). CHHV is explained, its origins, its impact on every disease, how it can be reduced, why there has been insufficient clinical research and how the Buteyko Method offers a practical solution.

Alexander Technique helps with Posture

ERGONOMICS… The term “ergonomics” is derived from two Greek words: “ergon,” meaning work, and “nomoi,” meaning natural laws. Ergonomists study human capabilities in relationship to work demands. POSTURE… In recent years, ergonomists have attempted to define postures which minimise unnecessary static work and reduce the forces acting on the body. All of us could significantly reduce our risk of injury if we could adhere to the following ergonomic principles: All work activities should permit the worker to adopt several different, but equally healthy and safe postures. Where muscular force has to be exerted it should be done by the largest appropriate muscle groups available. Work activities should be performed with the joints at about mid-point of their range of movement. This applies particularly to the head, trunk, and upper limbs.

Acupuncture studies by NCCAM

Introduction

Physical pain is a common occurrence for many People; in fact, a national survey found that more than one-quarter of U.S. adults had recently experienced some sort of pain lasting more than a day. In addition to conventional treatments, such as over-the-counter and prescription medications, people may try Acupuncture in an effort to relieve pain. This fact sheet provides basic information about pain and acupuncture, summarizes scientific research on acupuncture for specific kinds of pain, and suggests sources for additional information.

Key Points

• People use acupuncture for various types of pain. Back pain is the most commonly reported use, followed by joint pain, neck pain, and headache.
• Acupuncture is being studied for its efficacy in alleviating many kinds of pain. There are promising findings in some conditions, such as chronic low-back pain and osteoarthritis of the knee; but, for most other conditions, additional research is needed. The National Center for Complementary and Alternative Medicine (NCCAM) sponsors a wide range of acupuncture research.
• Acupuncture is generally considered safe when performed correctly.
• In traditional Chinese medicine theory, acupuncture regulates the flow of qi (vital energy) through the body. Research to test scientific theories about how acupuncture might work to relieve pain is under way.

Breast feeding develops Babies gut flora

A new University of Illinois study shows that human milk oligosaccharides, or HMO, produce short-chain fatty acids that feed a beneficial microbial population in the infant gut. Not only that, the bacterial composition adjusts as the baby grows older and its needs change.

Even though HMO are a major component of human milk, present in higher concentration than protein, many of their actions in the infant are not well understood. Furthermore, they’re virtually absent from infant formula. The scientists wanted to find out what formula-fed babies were missing.

“We refer to HMO as the fibre of human milk because we don’t have the enzymes to break down these compounds. They pass into the large intestine where the bacteria digest them.

Is Migraine all in your Head ?

IF YOU have ever absent-mindedly rubbed your eyes or nose after chopping up chilli peppers, you’ll have some idea of the suffering of one group of scientists in the name of medical research. A team at the Institute of Neurology in London have been injecting chilli juice into each others’ foreheads. Lab technician Paul Hammond, who got roped into the experiment, says it felt like acid was burning into his skin. “It was one of the most excruciating pains you can imagine,” he recalls.

The researchers weren’t sadomasochists, as far as we know. Their actions were part of a much larger research effort that has been shedding light on migraine. For although in the past few decades we have learned a great deal about the condition, we still have no idea of its root cause. And while we have drugs that help some patients, some of the time, understanding the underlying defect is the best way to boost our chances of discovering a sure-fire cure.