A bacterial cocktail could soon offer a knifeless alternative to gastric bypass surgery.
The gastric bypass limits a person’s food intake by, in effect, reducing the size of the stomach – often to the size of a walnut. The procedure is an effective treatment for obesity and associated diseases such as type 2 diabetes, and typically leads to a loss in excess body weight of between 65 and 75 per cent. However, it carries a high mortality risk, especially in severely obese individuals.
Lee Kaplan at Massachusetts General Hospital in Boston and colleagues may have discovered an alternative to surgery. The team performed a gastric bypass on mice and then fed microbes from their lower intestine to other healthy mice. The mice fed the bacterial cocktail lost five per cent of their body weight in two weeks, compared with mice on the same diet who had not been fed the bacteria. Continue reading Gut Bacteria swap is alternative to Gastric Bypass Surgery
The amount of salt in our diet could be involved in driving our own immune systems to rebel against us, leading to diseases such as multiple sclerosis, early laboratory findings suggest.
Several teams of scientists have simultaneously published data in the journal Nature suggesting a link.
Salt may activate a part of the immune system which can target the body.
Experts said the findings were very interesting and plausible, but were not a cure for people with MS.
The body’s defence against infection can go horrible awry, turning on the body and leading to autoimmune diseases including Type 1 diabetes, rheumatoid arthritis and multiple sclerosis. Continue reading Salt linked to “Immune Rebellion”
WEIGHT gain bugging you? Evidence is mounting for the central role that bacteria play in causing obesity.
Liping Zhao and his team at Shanghai Jiao Tong University in China put a morbidly obese man on a diet of whole grains, traditional Chinese medicines, probiotics and non-digestible carbohydrates for 23 weeks. The diet was designed to inhibit the bacteria thought to be associated with weight gain by increasing the pH in the colon.
The 175-kilogram volunteer lost 51 kg, despite not exercising. People who have had weight-loss surgery lose on average 49 kg. Continue reading Gut-microbe swap changes Eating Habits
Feeding faeces to people with chronic infection can cure them, but who wants to eat poo? A synthetic alternative could provide a more palatable option.
Hospital superbug Clostridium difficile can wreak havoc in the guts of vulnerable people, especially those who have lost some of their protective gut flora as a result of antibiotic use. Once it takes hold, the bacteria can cause nasty diarrhoea and in some cases is fatal. The usual treatment for the infection, which affects over half a million people in the US each year, involves a strong course of antibiotics. But the infection returns in about 20 per cent of cases, and some people become chronically infected. Continue reading Faecal Bacteria Cocktail treats superbug Infection